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Michael A. Mackey, Ph.D.
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Associate
Professor
Biomedical Engineering
2318,
Seamans Center
University
of Iowa
Iowa
City, IA 52242
Ph.
(319) 335 6058
Fax.
(319) 335 5631
michael-mackey@uiowa.edu
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Related Links
Detailed
Personal webpage
Research
@ UIBME
Research
Interests
- Nonequilibirum
thermodynamic theory of living systems
- Characterization
of the mathematical nature of intracellular motion
Education
- A.B.
1983 in biophysics, University of California, Berkeley
- Ph.D.
1988 in biophysics, University of California, Berkeley
and San Francisco Graduate Division
Professional
activities
- 1982
- 1983: President's Research Fellow, University of
California, Berkeley
- 1983
- 1987: Research Assistantship, Radiation Oncology
Lab, University of California, San Francisco, CA
- 1987
- 1989: Research Associate, Washington University
School of Medicine, Mallinckrodt Institute of Radiology,
Radiation Oncology Center, Section of Cancer Biology,
St. Louis, MO
- 1989
- 1991: Instructor, Washington University School of
Medicine, Mallinckrodt Institute of Radiology, Radiation
Oncology Center, Section of Cancer Biology, St. Louis,
MO
- 1992
- 2000: Assistant Professor, Washington University
School of Medicine, Mallinckrodt Institute of Radiology,
Radiation Oncology Center, Section of Cancer Biology,
St. Louis, MO
- 1998
- present: Associated Scientist, Istituto Nazionale
di Fisica Nucleare (Italian Institute of Nuclear Physics)
- 2000
- present: Associate Professor, Departments of Biomedical
Engineering and Radiology, University of Iowa, Iowa
City, Iowa
Selected
Publications
- Ahmad
IM, Aykin-Burns N, Sim JE, Walsh SA, Higashikubo
R, Buettner GR, Venkataraman S, Mackey MA, Flanagan
S, Oberley LW, and Spitz DR: Mitochondrial O2•-
and H2O2 Mediate Glucose Deprivation-Induced Cytotoxicity
and Oxidative Stress in Human Cancer Cells. J Biol
Chem 280, 4254-4262, 2005.
- Erenpreisa J, Kalejs M,
Ianzini F, Kosmacek EA, Mackey MA, Emzinsh D, Cragg,
MS, Ivanov A, and Illidge
TM: Segregation of genomes in polyploid tumor cells
following mitotic catastrophe. Cell Biol Int 29,
1005-1011, 2005.
- Yang F, Mackey MA, Ianzini F, Gallardo
G, and Sonka M: From 2D to 3D: Cell segmentation,
tracking, and
mitosis detection using temporal context. Lecture
Notes in Computer Science 3749, 302-309, 2005.
- Ianzini
F, Bertoldo A, Kosmacek EA, Phillips SL and Mackey
MA: Lack of p53 Function Promotes Radiation-Induced
Mitotic Catastrophe in Mouse Embryonic Fibroblast
Cells. Cancer Cell Int 6, 11, 2006.
- Coskun
H, Li Y, and Mackey MA: Amoeboid cell motility: “A
model and inverse problem, with an application to
live cell imaging data,” J Theor Biol, 244,
160-179 , 2007.
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